Research

Follow our publications on Dr. Stark’s google scholar, and also make sure to check out the free texts of all publications in our resources & paper copies tab

We often use technology and videoconferencing for our research. Here’s a short talk by Dr. Stark about some of this and a free copy of the paper including some of our best practices. See the Consulting page if you’d like to work with Dr. Stark on designing or visualizing a remote design when conducting research with persons with aphasia!



Research Topics

Overview

The lab evaluates how aphasia impacts spoken discourse (language beyond the sentence level) and, more globally, communication, via three inter-related focus areas: (1) characterizing language produced during spoken discourse using neuropsychological and neuroimaging methods; (2) identifying the extent to which spoken discourse is supplemented by gesture; and (3) examining how preserved inner speech (our inner narrative) supports aphasia recovery. This research increases understanding of the fundamental aspects of spoken language and communication from an interdisciplinary perspective by leveraging theory and methodology derived from neuroscience, linguistics, communication sciences and disorders, and cognitive science. Our research is translational, having the potential to improve aphasia management by better understanding prognostic factors (e.g., brain damage associated with language impairments, inner speech’s role in predicting language recovery) and strategies that improve communication (e.g., use of gesture).

Click the link to be taken to a page with more information, as well as relevant publications and multimedia presentations from our lab on the topic.

Inner Speech

Inner speech is the internal dialogue (or, monologue) we engage in with ourselves. “Inner speech” has been called a variety of things: inner (or internal) monologue, inner (or internal) dialogue, inner voice, covert (or silent) self-talk, internal narrative, verbal thinking, endophasia, autocommunication, and so on. We prefer the term 'inner speech' because it emphasizes the active nature of the phenomenon and does not presume about features, e.g., whether it is a monologue or dialogue. Interestingly, some of the population does not experience inner speech and those that do tend to vary in how often they engage with inner speech, and for what purposes. Inner speech has long been studied through interdisciplinary lenses (philosophy, neuroscience, linguistics, psychology), and therefore many methods and designs have been used to explore it. While it has most typically been explored in cognitively healthy young adults, our lab has a particular interest in studying inner speech in persons with post-stroke aphasia, a language disorder, because it may be intact compared to aloud speaking or even comprehension abilities.

Spoken Discourse

Spoken discourse is language used for a specific purpose, and is speech that goes beyond the sentence level. For example, you might tell a story about what you did last night — that’s spoken discourse! The goal of this research line is to integrate spoken discourse analysis into typical language assessment because, at present, analyzing discourse is not standard in clinical or research. the bulk of language and communication assessment in aphasia. Analyzing discourse enables simultaneous investigation of language structure (phonology, morphology, syntax, semantics, and pragmatics), dimensions of use (form, content, context), and multimodal strategies (gesture, eye gaze), lending a robust and comprehensive view of language and communication. During discourse, individuals with aphasia are enabled to speak on topics that are important to them. This establishes an inclusive and salient means of understanding communication ability. Finally, analyzing discourse may be a more sensitive means of establishing communicative competence across the aphasia severity spectrum. For example, discourse assessment identifies residual, subtle language impairments in the mildest forms of aphasia and then provides critical evidence for the receipt of continued clinical services to these individuals, many of whom want to rejoin the workforce. Our lab is very interested in how context and retelling affects discourse, and how discourse best practices (analysis, acquisition) can be improved.

Communicative Gesture

The short-term goal of this line of research is to understand how gestures improve communicative competence, which is the ability to successfully participate in the world using any verbal and non-verbal means. The long-term goal is to build assessments that enable quantification of gesture’s role in improving communication over time. Gesture appears to be remarkably intact in most individuals with aphasia, even in the presence of limb weakness or paralysis.

Brain Bases of Language and Language Recovery

My clinical neuroscience research moves the neurobiology of language field forward by examining the neural mechanisms and structures related to impaired language processes during discourse, and prior research has focused on evaluating brain bases of language recovery in chronic aphasia. Most of the research used to establish a neurobiology of language evaluated relationships between brain damage and impaired, isolated language processes (e.g., naming). Discourse is important to evaluate because the cognitive components required for lexical retrieval in this environment are more complex than in the isolated environment: future and past lexical alternatives must be suppressed during discourse, while other processes, like syntax, occur in parallel. Therefore, by evaluating discourse impairments and their relationship to brain damage, my research provides complementary and novel evidence for theory-building in the neurobiology of language. I typically utilize structural and functional MRI to investigate brain bases of language impairment and recovery.

 

Scroll down to learn about how we’re funded, our equipment and facilities, and a sampling of student research!



 
 
 


Research Facilities

We are located within Indiana University’s Department of Speech, Language and Hearing Science

We work closely with Clinical Faculty in IU’s Speech-Hearing Clinic

Address:

2631 E Discovery Parkway

Bloomington, IN 47408

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We collaborate closely with faculty and research scientists at Indiana University’s Psychological and Brain Sciences (PBS) Department

PBS houses our MRI facilities (Imaging Research Facility), including a 3T Siemens Prisma MR scanner

Address:

1101 E 10th St

Bloomington, IN 47405

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Top

Student Research

These are a few examples of the wonderful student-led research coming out of the lab!

Undergraduate Bella Buehler, who is interning in the lab through the Indiana University Center for Women & Technology’s (CEW&T) Women in STEM Research Experience presents her research at the CEW&T annual poster presentation.

Undergraduate Honors Thesis students Bethany Yagoda and Allison Harris present their research at the Indiana Speech-Language-Hearing Association Annual Meeting (2024) evaluating semi-structured interviews about inner speech, collected from persons with aphasia as part of a larger study, sponsored by NIDILRR.

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Sam Flores (a Groups-sponsored scholar) and Grace Oeding (a Hutton Honors-sponsored scholar for the summer) worked together to evaluate reliability of coding gesture in speakers with aphasia.

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Melissa Gunlogson successfully defended her MA Honors Thesis in 2021. The purpose of this study was to investigate the communicative role and rehabilitative potential of gestures in persons with chronic aphasia. During three narrative tasks, we evaluated communicative gesture types (co-speech [occurring with speech] and no speech [occurring in the absence of speech]) and function (adding [disambiguating, adding, or replacing speech] and redundant [with speech]). We then compared the coded data of gesture type and function to linguistic, demographic, and brain factors (specifically, damage to left Broca’s area [comprising inferior frontal gyrus pars opercularis and pars triangularis] and the left medial temporal gyrus [MTG]). We found not only that PWA produce a variety of gestures serving a communicative function, but also used gesture to compensate and potentially supplement deficits in speech. Brain damage (specifically, lesion in Broca’s area), aphasia severity, and nonfluent type aphasia all significantly predicted an increased proportionate use of no speech gestures and gestures which added information.

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Ellen Giudice successfully defended her Undergraduate Honors Thesis in 2021. Language changes occur in people experiencing neurodegenerative disease. However, it remains unclear how language changes are specific to neurodegenerative disease, how language shifts over the course of the disease, and how each task used to elicit speech (e.g., picture description, verbal fluency) uniquely demonstrates these language changes. The present study leveraged a preexisting database (DementiaBank) and evaluated the extent to which language dysfluencies were different by subject group (control group, Alzheimer’s Disease, Mild Cognitive Impairment), by task, and over time. Further discussion will take place on what differences were identified when looking across the different tasks. A main conclusion was that it is clinically important to assess language by using different tasks because unique language dysfluencies likely result because of differences in cognitive processes involved in each task.

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Darbi Ruff successfully defended her MA Honors Thesis in 2021. The purpose of her study was to analyze and evaluate personal network changes in the under-represented population of caregivers of acquired communication disorders. She used a convenience survey sample methodology to evaluate personal networks before a loved one’s event and after (i.e., present day) for caregivers of acquired communication disorders. Analyses revealed significant changes in network size, closeness, family/friend representation, and communication frequency between pre- and post-networks. Potential explanatory variables from life impact reports were evaluated for these network changes. This pilot study demonstrated consistencies and divergences in caregivers’ network changes and life impact compared to other caregiver or patient

 

Evaluating the relationship between executive functions, spoken discourse, and psychosocial outcomes in aphasia

Manaswita Dutta (PhD, ‘20) conducted her dissertation study examining the relationship among executive functioning, spoken discourse abilities, and life participation in persons with aphasia. Twenty-two individuals with chronic aphasia and 24 age- and education-matched healthy controls participated. All individuals completed (1) cognitive-linguistic assessments including an aphasia battery, comprehensive verbal and non-verbal executive functioning test battery, and a story retelling task, and (2) assessments evaluating aphasia-related life participation and psychosocial outcomes. Preliminary results indicated that persons with aphasia demonstrated verbal and non-verbal executive functioning and micro- and macro-linguistic spoken discourse difficulties, which negatively impacted their social participation and quality of life. These findings support the need to address executive functioning and spoken discourse in aphasia assessment and intervention and emphasize the importance of incorporating measures (beyond impairment-based language assessments) that allow identifying barriers and evaluating activity and participation-related outcomes in persons with aphasia.

This work was accepted for presentation at the Clinical Aphasiology Conference, the International Aphasia Rehabilitation Conference, and the British Aphasiology Conference in Spring 2020.

EVALUATION OF A NEW VISUAL SCALE FOR MEASURING MOOD IN APHASIA: RELATIONSHIP WITH VALIDATED SCALES AND PERCEPTION OF UTILITY

Madison Neumann (MA, ‘20). Depression and mood-related issues are common in aphasia. Many mood assessments rely on complicated language, making them difficult to use in moderate-severe aphasia. Visual analog mood scale (VAMS) has been used to measure mood without use of language in aphasia. A dynamic visual analog mood scale (D-VAMS) has been proposed to be a more sensitive measure. In N=6 controls and N=10 people with aphasia (as a result of acquired brain damage), this study aimed to 1) compare the relationship of D-VAMS scores to VAMS scores; 2) identify differences in perceived utility of the two mood measures; 3) elucidate the relationship of a common measure of depression (Patient Health Questionnaire-9) with D-VAMS rating; and 4) investigate the relationship between emotion perception and the utility of a mood measure that uses human faces (D-VAMS).


About MRI

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Dr. Stark’s brain!

 

introduction to mri

Magnetic resonance imaging (MRI) is a very safe methodology, which uses a powerful magnetic field, radio waves and a computer to produce detailed pictures of the brain and other cranial structures that are clearer and more detailed than other imaging methods. MRI does not use ionizing radiation (e.g. x-rays).

Why we do MRI

We take detailed pictures of your brain while you rest as well as while you do a task. We are interested in the areas of your brain (structure) and how the areas of your brain work together to do tasks (function).

our Mri

We have a 3 Tesla MRI system made by Siemens. It is located in our Psychological and Brain Sciences Department, 1101 E 10th Street. We’ll provide you with more detailed instructions when you schedule to participate.

What you will do in the MRI

For the first five minutes, we will take a detailed picture of your brain. Then, you will participate in a few tasks, which we will go over outside of the scanner. After this, you will be allowed to relax and close your eyes as we take more detailed pictures. The entire scan lasts just under an hour.

MRI Safety

When you come to our lab, we’ll give you an MRI screening form to fill out. You’ll also be asked about possible contraindications (e.g. things that might not be ideal to go into an MRI) when we do pre-screening. MRI is a very safe methodology and it remains safe because we, as trained operators of the scanner, take precautions against undue risk. For example, we will carefully identify any metal that you may have in or around your body. Not all metal implants are safe for an MRI, and we verify this before we schedule you for a scan. We also make sure that you take all of the metal off of your person prior to entering the scanner room. There are always two individuals in the scanner operating room, both trained in safety of MRI scanning. Dr. Stark has been doing MRI scans since 2012.

While the MRI is safe, some adverse events occur, albeit rarely. Sometimes, heating of skin can happen. This typically occurs when the skin is in contact with metal, or when there is metal in tattoos or a piece of metal has not been taken off of your person. As described above, we take great precautions to make sure that you are MRI safe before entering the scanner. Should we find anything that looks out of the ordinary on your brain scan, we are obligated to send the scan to the IU Health radiologists. We call these ‘incidental findings.’ We will not be privy to those results; radiologists will contact you directly. Should we find something out of the ordinary such as this, we will tell you and we will stop the scan. This is, again, a rare occurrence.

What to expect when you come for the MRI

It is best to wear comfortable clothes without metal (e.g. bra without underwire, loose clothing). You’ll meet one of our lab members ahead of the scan to go over any questions you have as well as the tasks you’ll be doing in the scanner. You’ll then be asked to fill out another MRI safety screening form and the operator of the scanner will go over this form with you to ensure that you are safe to enter the scanner room. You’ll leave any removable metal objects (e.g. wallet, phone, belt) outside of the scanner in a safe place.

A view of the head coil

A view of the head coil

Body positioning with the head coil on

Body positioning with the head coil on

In the scanner: You will lie down on your back on a bed and a head coil will be placed over your face and head. This is the radio signal, by which we get very crisp pictures of your brain (see photo on right). The bed will then be raised and slowly pushed back into what we call a bore, i.e. the entrance of the scanner. Your body above your knees will be in this scanner bore. You’ll be equipped with a squeeze button, which you can press to alert us of any issue or any question. We have an intercom system with which we’ll talk to you throughout. You’ll wear ear protection and your head will be surrounded by styrofoam to dampen the noise and to make sure your head stays in the same position throughout the scan. You will also be given a leg rest to make lying on your back more comfortable. Scans are very susceptible to movement, so we ask that you remain very still when scanning is occurring. You will also receive a response device (e.g. buttons to press) for when you are asked to do the tasks that you practiced outside of the scanner.

It is typical for the scanner to make loud sounds as it takes pictures of your brain as well as the bed to slightly move throughout the scan. The sound and movement will change dependent on the type of image that we’re acquiring. This is all very typical. Some people report feeling ‘tingles’ throughout some scans, though this is rare. If, at any point, you should be uncomfortable, you are encouraged to press the squeeze ball. You will be provided a CD of your brain scan at the end of the session. We keep all brain scans on file for at least seven years, as per our Institutional Review Board obligation - therefore, should you ever need to send these brain scans to a neurologist or similar medical provider, please reach out to us and we will facilitate this process.

Helpful multimedia about MRI

A quick video showing one kind of brain scan we acquire from the MRI: https://www.youtube.com/watch?v=0LupvsT87Ec

More about MRI, including safety considerations (removing metal from your body, etc): https://www.youtube.com/watch?v=MkmfQOET4pc

A very similar model to our own MRI scanner

A very similar model to our own MRI scanner

*** bear in mind we go in head-first, as we are only interested in taking pictures of the brain.

While this webpage is meant to be kid-friendly, it has great, easy to understand information about MRI: https://kidshealth.org/en/parents/mri-brain.html